After making a harsh lunge on Crystal Palace winger Wilfred Zaha in their most recent encounter, the former Real Madrid midfielder received his fifth yellow card of the season and was suspended for United’s following meeting.
Donny Van De Beek and Axel Tuanzebe are also certain to be out with injuries, according to Ten Hag, while Anthony Martial and Diogo Dalot are questionable and will need to pass a last-minute fitness test to travel with the team to London.
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Jack Butland will be back in the lineup after being out the last time out. David De Gea is expected to stay in goal and was unfortunate to concede a last-second goal against Palace after making numerous outstanding saves to hold the Eagles at bay.
The four man defense will still consist of Raphael Varane and Lisandro Martinez in the centre, with Luke Shaw and Aaron Wan-Bissaka filling the left and right back positions.